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4 Best Acetyl L-Carnitine Supplements Compared for 2025

Emma-Kate Lidbury

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Acetyl L-carnitine (a form of L-carnitine) is an amino acid derivative that helps transport fatty acids into mitochondria for energy production. It crosses the blood-brain barrier efficiently, supporting brain function by enhancing mental clarity, memory, and focus.


Research suggests it may benefit cognitive health by acting as a neuroprotective agent and potentially boosting neurotransmitters like acetylcholine.


This 2003 meta-analysis showed the benefits of acetyl l-carnitine supplements on the treatment of mild cognitive impairment and mild Alzheimer’s disease. It can also help support thyroid hormones, heart health, liver function, and kidney support.


This guide compares the top acetyl l-carnitine supplements. You're likely to discover these brands as you're researching the top options on the market, so this guide is designed to help you compare the key product details (like third-party testing and dosage), as well as the pros, cons, and pricing.


We'll start the list of the best options with our own acetyl l-carnitine product at Momentous.

1. Momentous Acetyl L-Carnitine

Key Things to Know About This Product

  • Third-Party Tested: Yes, NSF Certified for Sport

  • Money-Back Guarantee: Yes

  • Gluten Free: Yes

  • GMO Free: Yes


Product Details:

  • Price: $26.95

  • Number of Servings: 60

  • Amount of acetyl l-carnitine per serving: 500 mg

  • Serving Size: 1 capsule

  • Subscription: Yes - 25% discount on first order, 10% thereafter

  • Free shipping: Yes (orders over $75)


Pros:

  • Third-party certified - NSF Certified for Sport

  • Single-ingredient formulation and dosage based on the latest clinical research

  • High quality and purity


Cons:

  • Price

I’ve been using  Momentous Acetyl L-Carnitine for a few months now, and it’s one of the few supplements I’ve stuck with long-term. I originally picked it up to help with mental performance and afternoon brain fog, and it’s definitely helped me stay more focused and improved my cognitive function throughout the day. I feel sharper during deep-work sessions and more mentally resilient when I’m juggling a lot. Some people also report better mood and exercise performance while using it.


The NSF Certified for Sport® certification gives me real peace of mind knowing it’s free from contaminants and banned substances. I also appreciate that the formula is clean — just pure acetyl L-carnitine at a clinically effective dose with no unnecessary extras.


The benefits weren’t immediate, but after about two weeks of daily use, I started noticing more sustained energy, especially during workouts and long writing sessions. This is one of the reasons why it is popular with endurance athletes also. For me, it’s not a “quick fix” supplement, but one that builds up in effectiveness with consistent use.


If budget is your most important factor, you might prefer some of the other products mentioned below as it’s one of the more expensive options. Yet with The Momentous Standard and the rigorous sourcing, testing, and certifications that Momentous products undergo, in my opinion, the price is well worth it.


This is a great product for anyone looking to support enhanced mental function, better brain health, clean energy and recovery, and central nervous system support—whether you're an athlete, a creative, or someone who just wants to feel more “on.” 

2. NOW Acetyl-L-Carnitine

Key Things to Know About This Product

  • Third-Party Tested: Yes, GMP (Good Manufacturing Practices)

  • Money-Back Guarantee: Yes

  • Gluten Free: Yes

  • GMO Free: Yes


Product Details:

  • Price: $29.99

  • Number of Servings: 100

  • Amount of acetyl l-carnitine per serving: 500 mg

  • Serving Size: 2 capsules

  • Subscription: No

  • Free shipping: Yes, on orders $50+


Pros:

  • Cost effective

  • Gluten free and GMO free


Cons:

  • No NSF Certified for Sport certification

NOW Acetyl-L-Carnitine is a budget-friendly way to support focus and energy levels throughout the day. The 500 milligrams (mg) capsules are easy enough to take, and many customers enjoy that they’re non-GMO, gluten-free, and made without common allergens. NOW products also follow current Good Manufacturing Practices (GMP), which ensures products are consistently produced and controlled according to quality standards, although it lacks the NSF Certified for Sport certification that some higher-end options carry.


These capsules are available in 50-capsule, 100-capsule, or 200-capsule options, with the latter providing the best value for money and is easily one of the most cost-effective acetyl-l-carnitine options on the market.


If you're someone looking to try acetyl l-carnitine for cognitive or metabolism support while keeping costs down, NOW’s version is a solid, reliable choice. While it may not have all the third-party certifications of premium brands, it covers the essentials and delivers consistent results.

3. Thorne Acetyl L-Carnitine

Key Things to Know About This Product

  • Third-Party Tested: Yes, NSF Contents Certified 

  • Money-Back Guarantee: Yes

  • Gluten Free: Yes

  • GMO Free: Yes


Product Details:

  • Price: $30

  • Number of Servings: 60 capsules

  • Amount of acetyl l-carnitine per serving: 500 mg

  • Serving Size:  1 capsule

  • Subscription: Yes - save 20%

  • Free shipping: Yes - on all orders


Pros:

  • Third-party tested

  • High quality and purity


Cons:

  • Price


As with the Momentous product, Thorne’s Acetyl L-Carnitine is a premium product that is third-party tested and used and trusted by professional athletes and weekend warriors alike. Customers report feeling a noticeable difference in mental acuity and physical energy levels after a few weeks of consistent usage. You can also rest assured that you’re getting a product that is safe, pure, potent, and effective.


It is worth noting that this Thorne product carries the NSF Contents Certified certification whereas the Momentous product is NSF Certified for Sport. The difference is small but significant, especially for athletes. NSF Contents Certified means the contents have been tested to ensure they do not contain unsafe levels of contaminants and to verify label claims. The Certified for Sport certification covers this as well as testing for prohibited substances or masking agents.


The capsules are small and easy to take, with no unpleasant aftertaste or smell, which is a big plus compared to some other acetyl-l-carnitine supplements. At 500 mg per capsule, the dose is right where it needs to be.


The only downside to this product is the price. At $30 for 60 capsules, it’s the most expensive option reviewed here, but many prefer paying extra for the peace of mind that comes from purchasing from a reputable brand that undertakes third-party testing. If you’re on a leaner budget, it might not be the option for you.

4. Jarrow Formulas Acetyl L-Carnitine

Key Things to Know About This Product

  • Third-Party Tested: Yes, Non-GMO Certified & GMP

  • Money-Back Guarantee: Yes

  • Gluten Free: Yes

  • GMO Free: Yes


Product Details:

  • Price: $20.24

  • Number of Servings: 60

  • Amount of acetyl l-carnitine per serving: 500 mg

  • Serving Size: 1 capsule

  • Subscription: Yes - save 5%

  • Free shipping: No


Pros:

  • Cost effective

  • Certified non-GMO

  • Vegan-friendly and free from common allergens


Cons:

  • Not NSF-certified

  • No free shipping incentives

  • Lower subscription discount


At just over $20 for 60 capsules, Jarrow Formulas Acetyl L-Carnitine is one of the more cost-effective options on the market if you’re looking to enhance your mental clarity and better support your energy levels. Most users note feeling improvements within a few weeks of consistent supplementation.


Many customers also enjoy the fact that it's vegan-friendly and free from common allergens like gluten, soy, and dairy.


Although Jarrow follows current Good Manufacturing Practices (GMP), it does not undertake third-party testing like Momentous or Thorne, so the lower price tag can mean less peace of mind. The shipping and subscription options are also less enticing than other brands. Overall, though, it’s a reliable choice for those looking for a wallet-friendly option. 

Emma-Kate Lidbury

Emma-Kate Lidbury

Emma-Kate Lidbury is a freelance writer and editor with 20 years of experience working in the health and fitness world.