Apigenin is a bioflavonoid compound found in various fruits, vegetables, and herbs, such as chamomile and parsley, which can help reduce stress and promote higher-quality sleep. Apigenin works by activating chloride ion channels, calming overall neuronal activity in the forebrain, and allowing the body to enter a more restful state. Research has also demonstrated that apigenin can decrease the stress hormone cortisol.
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Everything at a Glance
- Helps increase total sleep duration
- Promotes relaxation and faster onset of sleep
- Helps alleviate feelings of stress
- Demonstrates antioxidant and anti-inflammatory effects
Take 1 capsule 30-60 minutes prior to sleep
- Interacts with various molecular targets in the body, including neurotransmitter receptors and signaling pathways
- Binds to receptors in the brain and can help to reduce feelings of stress and promote higher-quality sleep
- Activates chloride ion channels which calm overall neuronal activity in the forebrain, allowing the body to enter a more restful state
- Research has also demonstrated that apigenin can also decrease the stress hormone cortisol
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Several plant bioactive compounds have exhibited functional activities that suggest they could play a remarkable role in preventing a wide range of chronic diseases. The largest group of naturally-occurring polyphenols are the flavonoids, including apigenin. Higher dietary intake of certain polyphenols may be associated with better sleep quality among adults. Additionally, studies have shown that apigenin increases total sleep duration as well as quickens sleep latency.
Apigenin has been extensively studied, and emerging research supports its potential benefits. Studies have shown that apigenin activates chloride ion channels, promoting restful sleep and faster sleep onset. Research has also indicated that apigenin can decrease cortisol levels, contributing to stress reduction and relaxation. Numerous other studies have investigated its effects on cognitive function, stress reduction, and overall health. These studies suggest that apigenin can enhance memory, improve learning ability, reduce anxiety and depression-like behaviors, and provide antioxidant and anti-inflammatory effects. However, further research is ongoing to fully understand its mechanisms of action and potential applications.
From Dr. Andrew Huberman, host of the Huberman Lab podcast
"There's another supplement that could be quite useful, which is Apigenin, which is a derivative of chamomile, 50 milligrams of apigenin can augment or support sleepiness to help fall asleep and stay asleep."
What to Expect With Apigenin
When to Use
Ingredients We Can Be Proud of
Frequently Asked Questions
No, Apigenin is not habit-forming or addictive. It is a natural compound that supports healthy sleep and stress management without causing dependence.
Yes, Apigenin is part of our three ingredient blend for Sleep Pack which includes Magnesium Threonate and L-Theanine. While Apigenin is generally safe to use with other supplements, it's advisable to consult with a healthcare professional to ensure compatibility and avoid any potential interactions.
Individual responses may vary, but most users experience improved sleep quality and reduced stress within a few weeks of consistent use. For optimal results, we recommend using Apigenin as part of a holistic sleep routine that includes good sleep hygiene protocols.