Berberine
60 Servings Per Container $/Serving
Clinically-validated, naturally-occurring compound in a 9.6x more bioavailable form for metabolic health.
- Activates pathways for optimal energy usage
- Promotes cardiovascular health
- Improves cellular and mitochondrial efficiency
Frequently Purchased Together
Bioavailable Support for Metabolic Health
Our Berberine, featuring Berbevis®, is 9.6x more bioavailable than standard berberine and helps your body convert fuel into usable energy more efficiently.
Berberine promotes smarter energy use, steadier metabolism, and a more efficient foundation for performance.
This formula works at the cellular level to improve how your body regulates and sustains energy production. Berberine supports metabolic efficiency and nutrient utilization — helping your cells convert food into energy more effectively — and helps maintain cardiovascular wellness by promoting healthy cholesterol balance.
The Berbevis® Phytosome™ delivery system combines Berberis aristata root extract with pea protein, sunflower lecithin, and grape seed extract to enhance absorption and stability. The result: improved bioavailability, better tolerance, and consistent metabolic benefits you can feel.
Supports Metabolic Efficiency
Berberine activates AMPK (AMP-activated protein kinase), the body’s central energy regulator. This pathway controls how cells convert nutrients into usable energy and helps maintain metabolic balance under varying energy demands. By influencing this master switch, Berberine supports healthy glucose metabolism and promotes efficient energy utilization across multiple systems. Clinical research on Berbevis® utilizing the Phytosome™ delivery system shows this bioavailable form significantly enhances cellular uptake, amplifying AMPK’s metabolic effects with improved absorption and better tolerability.
Promotes Cardiovascular Health
Berberine may support cardiovascular health by influencing key pathways responsible for lipid balance. It has been shown to promote healthy cholesterol levels by supporting LDL receptor activity and helping regulate PCSK9—mechanisms that play a central role in how the body clears and manages circulating lipids. Clinical research on Berbevis® utilizing the Phytosome™ delivery system shows significant improvements in total cholesterol, triglycerides, HDL ratios, and oxidative stress markers, indicating broad support for long-term heart and vascular wellness.
Enhances Mitochondrial Function
At the cellular level, Berberine supports mitochondrial performance—the process by which cells generate ATP, the body’s energy currency. This mechanism helps sustain steady energy output and improve cellular efficiency over time. Enhanced mitochondrial function contributes to metabolic resilience by reducing energy waste and supporting optimal performance under physical or metabolic stress. The Berbevis® Phytosome™ delivery system improves mitochondrial bioavailability, delivering measurable benefits with smaller, more effective doses.
Take 1-3 capsules daily or as recommended by your healthcare practitioner.
Recommended to take right before a meal. If taking multiple per day, take a single capsule before each meal.
Berbevis® Berberine Phospholipid (Berberis aristata root extract and Phospholipid Combination with pea protein isolate, sunflower lecithin, and grape seed extract)
Other Ingredients: Hypromellose (Capsule), Microcrystalline Cellulose, Calcium Silicate, Magnesium Stearate, Silica.
Our Berberine features Berbevis®, utilizing a next-generation Phytosome™ delivery system, designed for superior absorption and long-term tolerability.
- More Soluble: Berberis aristata extract is more soluble than standard berberine, enhancing its effectiveness.
- Optimized Absorption: Pea proteins in the Phytosome™ matrix improve berberine bioavailability, as shown in scientific research.
- Gentle on the Gut: Grape seed extract protects the intestinal lining and reduces gastrointestinal side effects for better comfort and tolerability.
- Sourcing: The Berberis aristata root is wild harvested in India.
When to Use: Daily, before meals.
Onset Time: Many users feel noticeable improvements in energy stability and digestion within 2–4 weeks.
Ongoing: Sustained metabolic efficiency and recovery support.
There are 6 credible reviews and studies related to this product:
Berbevis (trademarked ingredient)
- Berberine formulated as Berbevis® utilizing the Phytosome™ delivery system delivers 9.6× better absorption
- In people with higher than normal fasting blood sugar, Berberine formulated as Berbevis® improved glucose levels compared to placebo.
- The berberine group showed significant reductions in total cholesterol and triglycerides, along with an increase in HDL cholesterol compared to the SM-only group.
- People taking Berberine formulated as Berbevis® utilizing the Phytosome™ delivery system alongside common medications (like blood thinners, blood pressure drugs, thyroid meds, and metformin) showed no negative interactions with excellent tolerability.
- Specific to women with PCOS: 70% of women taking Berberine Phytosome regained regular menstrual cycles (vs 16% in the control group). Both groups followed the same diet, showing that Berberine Phytosome gave an extra boost.
Berberine (general)
- Helps regulate neurotransmitters like serotonin + dopamine
- Supports falling back asleep + promotes calm
- May reduce nighttime wakeups
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- Supports brain, heart, and joint health with no fishy aftertaste
- Aids recovery and reduces inflammation from training or stress
- NSF Certified for Sport® and tested for heavy metals and purity
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- Helps protect against oxidative stress and free radical damage
- Supports brain, heart, and metabolic function
- Ideal for long-term vitality and recovery from stress
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- 6 clinically-studied ingredients that work together
- Targets core cell functions - beyond just NAD⁺
- Promotes brain function + DNA integrity
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- Helps convert fat into energy. Supports mitochondrial health
- Supports focus, memory, and mental clarity
- Acts as an antioxidant to protect the brain from oxidative stress
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Frequently Asked Questions
Our Berberine is formulated as Berbevis®, which utilizes the Phytosome™ delivery system and delivers 9.6x greater absorption than standard berberine. The Berbevis® formula is more gentle on the gut for better comfort and tolerability, and the Berberis aristata root – which is wild harvested in India – is more soluble than standard berberine, enhancing its effectiveness. Additionally, our Berberine is NSF Certified for Sport® — a standard few brands meet.
Inositol
May help balance hormones and improve insulin sensitivity, especially for women—complementing Berberine’s role in supporting metabolic health.
Omega-3
Supports healthy triglyceride levels, heart function, and helps reduce inflammation—making it a great companion to Berberine’s metabolic and cardiovascular benefits.
Resveratrol
Works synergistically with Berberine to support healthy aging and cellular performance. While Berberine directly activates AMPK—the body’s master energy regulator—Resveratrol indirectly supports this same pathway through SIRT1 and NAD⁺ signaling, enhancing cellular energy, repair, and resilience.
Longevity
Builds the quality of your cellular “engine” by addressing oxidative stress and supporting mitochondrial health, while Berberine tunes the body’s fuel system through AMPK activation—together promoting efficient energy production and long-term vitality.
Acetyl-L-Carnitine (ALCAR) Pairs with Berberine to optimize fat and energy metabolism. As Berberine switches on metabolism through AMPK activation, ALCAR helps transport fats into the mitochondria—where they’re converted into energy—supporting endurance and cellular performance.
Our Berberine is formulated as Berbevis® utilizing the Phytosome™ delivery system — this means it is a berberine bound to phospholipids to improve absorption and tolerability, and it is supported by multiple human clinical studies demonstrating superior bioavailability (9.6x times more bioavailable) and metabolic benefits compared to standard berberine. Dihydroberberine (DHB) is a metabolite of berberine that’s naturally formed in the gut and absorbed more easily (5x more than standard berberine) due to its reduced, more lipophilic structure, though it currently has less extensive clinical validation despite promising preliminary research.
Many brands use berberine HCl, which has low absorption and can cause stomach issues. Our Momentous Berberine features Berbevis® utilizing the Phytosome™ delivery system, which has improved stability, bioavailability, and tolerability.
Berberine and Inositol both improve insulin sensitivity and metabolic health but work differently. Berberine is a plant-derived alkaloid, while inositol is a vitamin-like compound (sometimes called vitamin B8). Berberine activates AMPK to lower blood sugar, improve cholesterol, and support weight management, while Inositol enhances insulin signaling and hormone balance, particularly for PCOS and fertility. In short: berberine is better for metabolic control, inositol for hormonal balance, and together they can be complementary.
Yes, Momentous Berberine is vegan, gluten-free, and GMO-free.
Berberine can interact with several drug classes; it may intensify blood sugar–lowering effects of diabetes medications, inhibit liver enzymes that metabolize many drugs (raising their levels and side effects), and amplify the effects of blood pressure medicines and blood thinners.
As always, please consult your healthcare provider.
Yes. Our Berberine is NSF Certified for Sport®. NSF Certification ensures purity and potency, with every batch tested for heavy metals, harmful additives, and label claim accuracy to meet the highest standards.